Seroprevalence and Biomarkers Detection of Human Herpes Virus (HHV-8) in Patients with Kaposi Sarcoma
نویسندگان
چکیده
Kaposi's sarcoma (KS) represents the most prevalent malignancy among untreated HIV-positive individuals. Herpesvirus linked with (KSHV; also termed as human herpesvirus 8 (HHV8)). In this study, blood samples were collected from 120 individuals, 60 of them had HHV-8 infection kaposi and persons apparently healthy control. These patients attended Baghdad Teaching Hospital period 15th February 2021 to January 2022. Infections are seen be more in age group 25-49 years when compared other groups. The distribution biomarkers confirmed that 50, 25 80% 20 infected positive for Ca19.9, Ca125 Ca15.3 respectively. Ca125, all produced good results Human Herpes Virus (HHV-8) infections, leading us conclusion these gave favorable results. All PCR products showed a amplification at 434bp. Phylogenetic analysis belongingness HHV strain. Further, could lead development novel molecular diagnostic tool.
منابع مشابه
Immunohistochemical Detection of the Human Herpes Virus 8 (HHV8) Latent Nuclear Antigen-1 in Kapasi Sarcoma Cases
Background and Objectives: The molecular genetic of the human herpes virus 8 (HHV8) has now been characterized the pathogenesis of kaposi sarcoma (KS). This study attempted to determine the rate of HHU-8 infection in KS in an Iraniann cross sectional study. Method & material: In this cross-sectional study, we used paraffin-embedded specimens of 54 clinically well-characterized kaposi sarcom...
متن کاملسرواپیدمیولوژی ویروس هرپس هشت انسانی (HIV-8) در اهداکنندگان خون بیماران همودیالیزی و افراد HIV مثبت در شهر تهران
Background and Aim: Human herpes virus 8 (HHV-8), also known as Kaposi sarcoma-associated herpes virus, is believed to be the infectious trigger for Kaposi sarcoma. HHV-8 transmission takes place via different routes such as saliva, sexual intercourse, mucosal contact and possibly blood transfusion. The objective of this study was to determine HHV-8 seroprevalence in otherwise healthy blood don...
متن کاملAIDS: Acquired Immune Deficiency Syndrome HAART: Highly Active Antiretroviral Therapy HHV8: Human Herpes Virus 8 HIV: Human Immunodeficiency Virus HIV-KS: HIV associated Kaposi Sarcoma KS: Kaposi Sarcoma KSHV: Kaposi Sarcoma Herpes Virus
cAse rePOrts case no 1 A 33-year-old female of African descent was referred to the Oral Medicine Clinic from a neighbouring rural clinic. The patient presented with painful nodular lesions on her gingivae and hard palate, having noticed the enlarging lesions two months earlier when they started to impair her speech and mastication. She reported that she had been diagnosed with HiV infection two...
متن کاملKaposi's sarcoma associated herpes virus (KSHV/HHV 8): epidemiology, molecular biology and tissue distribution.
Introduction Although first described in 1872, Kaposi's sarcoma remains a neoplasm of uncertain histiogenesis.' The lesion is considered by some experts to be a vascular neoplasm and by others, a reactive vasoformative condition. Currently, the debate still rages over the precise cell of origin of Kaposi's sarcoma-that is, whether it is of lymphatic or true endothelial cell origin. Clinically, ...
متن کاملHuman herpesvirus 8 (HHV-8) detected in two patients with Kaposi's sarcoma-like pyogenic granuloma.
AIMS To report the finding of human herpesvirus 8 (HHV-8) in two patients with Kaposi's sarcoma (KS)-like pyogenic granuloma. This form of pyogenic granuloma closely resembles KS histologically and it has been reported that immunohistochemistry in such lesions may be positive for smooth muscle actin and factor VIII related antigen, which are typically negative in KS. In both patients the lesion...
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ژورنال
عنوان ژورنال: Journal of techniques
سال: 2023
ISSN: ['2708-8383']
DOI: https://doi.org/10.51173/jt.v5i2.857